* [DeskcommCRM v1.80.0](https://github.com/melgarafael/DeskcommCRM) – IA agents-based, self-hosted sales operating system that runs an open-source CRM with native WhatsApp sales, qualification, and conversation handling.

* [Open Mercato v0.9.0](https://github.com/open-mercato/open-mercato) – AI-supportive, modular framework for building enterprise-grade CRM, ERP, and commerce backends with customizable modules and multi-tenant support.

* [Twenty twenty/v2.46.0](https://github.com/twentyhq/twenty) – Modern CRM solution designed to improve user experience and reduce costs.

* [AlphOne v0.27.0](https://github.com/gopherium/AlphOne) – Plugin-first CRM with a Go JSON API backend and a React single-page application frontend.

* [BottleCRM v1.14.2](https://github.com/Django-CRM/Django-CRM) – Modern CRM platform built with a Django REST API backend and a SvelteKit frontend, using JWT authentication and a multi-tenant PostgreSQL RLS setup.

* [LINE Harness v0.24.2](https://github.com/Shudesu/line-harness-oss) – LINE Official Account CRM for step delivery, broadcasts, forms, rich menus, scoring, automation, and AI-assisted messaging.

* [Macro v2026.10.10.0](https://github.com/macro-inc/macro) – Unified team workspace combining email, messaging, tasks, calls, docs, CRM, and shared AI memory.

* [PowerX docker-dev-03a2a58c6...](https://github.com/ArtisanCloud/PowerX) – AgentOS-based platform for AI agents and CRM workflows, providing MCP, gRPC/REST, SDKs, IAM/RBAC, event bus, and DB/flow layers.